Studies

A large-scale observational study involving 1,268 patients who had both fresh and older scars showed that an improvement in scar condition and redness was possible within 2-3 months of 2x daily application of Contractubex^®. More than 80% of doctors and patients rated the effect of the treatment on scarring as good or very good. (1)

Another clinical trial examined the effect of Contractubex^® Gel in 107 patients who had a tattoo removed by laser treatment. Laser treatments are known to cause scarring. In the group that applied Contractubex^® Gel between treatments after wound closure, scars were found to form less frequently. (2)

A combination therapy of Contractubex^® Gel with therapeutic ultrasound* was examined in an observational study of 35 patients. In this combined treatment, Contractubex^® Gel was introduced into the scar tissue with the aid of ultrasonic waves.

Within five weeks of daily application of Contractubex^® Gel as well as supplementary treatment every third day with Contractubex^® Gel plus therapeutic ultrasound, the overall result improved. More than 80% of the patients and the treating physician described the success of the treatment as well as skin tolerability as good or very good. (3)

A clinical trial examined the effect on scarring after heart surgery in children and adolescents aged 1 to 18 years. After six months, the group treated with Contractubex^® Gel developed significantly less conspicuous scarring than the untreated group. Even after six further months without treatment, this significant difference between the two groups remained. (4)

^{(1) Willital, G.H. and J. Simon, Efficacy of Early Initiation of a Gel Containing Extractum Cepae, Heparin, and Allantoin for Scar Treatment: An Observational, Noninterventional Study of Daily Practice. J Drugs Dermatol, 2013. 12(1): p. 38-42}

^{(2) Ho, W.S., et al., Use of onion extract, heparin, allantoin gel in prevention of scarring in chinese patients having laser removal of tattoos: a prospective randomized controlled trial. Dermatol.Surg., 2006. 32(7): p. 891-896}

^{(3) Danneberg, D., Narbenspezialgel- rasche Effekte unter therapeutischem Ultraschall: Ergebnisse einer monozentrischen Untersuchung (Scarring special gel – rapid effects with therapeutic ultrasound: results from a monocentric study). Kosmetische Medizin – Cosmetic Medicine, 2007. 28(3).}

^{(4) Maragakis, M., et al. Possibilities of scar treatment after thoracic surgery. Drugs Exptl. Cin. Res. XXI(5) 199-206 (1995)}

^{* Therapeutic ultrasound should only be used by qualified personnel. The treatment is offered by doctors such as dermatologists or also by physiotherapists.}